MODE™: BISPECIFIC MOLECULES TARGETING PATHOGENIC CIRCULATING PROTEINS
Molecular degraders of extracellular proteins (MoDE™) are bispecific molecules that target pathologic circulating proteins and direct them to the liver (or other organ systems) for degradation by the endosomal/lysosomal pathway.
BHV-1300 is the lead asset using MoDE technology. BHV-1300 is a potent extracellular Pan-IgG lowering agent with an innovative mechanism of degrading and depleting pathogenic IgG rather than inhibition.
