GLUTAMATE

GLUTAMATE MODULATION PLATFORM

Our glutamate modulation platform is comprised of two product candidates: troriluzole (BHV-4157) and BHV-5000/5500. These work in the body to balance the glutamate system via two distinct mechanisms: glutamate transporter modulation (troriluzole) and N-methyl-D-aspartate, or NMDA, glutamate receptor antagonism (BHV-5000/5500). Troriluzole is currently in late-stage development for obsessive-compulsive disorder (OCD).

OCD Biohaven Clinical Trial

OBSESSIVE-COMPULSIVE DISORDER (OCD)

Efficacy and Safety Study of Adjunctive Troriluzole in
Obsessive-Compulsive Disorder

Drug: Troriluzole | Age: 18-65 | Phase: 3

GLUTAMATE PLATFORM PRODUCT CANDIDATES

DRUG

INDICATION

GLUTAMATE

2 STUDIES

Troriluzole

NCE prodrug of riluzole

Obsessive-Compulsive Disorder (OCD)

Disease Related to Glutamate Dysregulation